CN109288685A is a Chinese patent application reproduced in the source archive dental-enamel dossier under the title "Method and application for inducing fluoro-calcium silicate biomimetic mineralization based on amelogenin." It belongs to the field the dossier describes as biomedical materials.
Claimed subject matter
As quoted in the dossier, the invention discloses a method in which "fluoro-calcium silicate in mineralizing solution is induced by the amelogenin to form a biomimetic mineralization material." The method uses "the self-assembly capacity of the amelogenin," with fluoro-calcium silicate serving "as an inorganic bioactive material in the biomimetic mineralizing solution to build nano-sized and micron-sized biomimetic hard tissue mineralization layers."
The claimed result is that the formed mineralization layers are "superior to mineralization layers formed by pure inorganic ceramic bioactive materials," with "grain crystals... orderly arranged and grow in an orientated manner along a sizing shaft to form a nano-apatite grain crystal structure similar to bones and teeth."
Material distinction
This is an amelogenin system, not the elastin-like recombinamer matrix of the Nature Communications paper. The two should not be conflated, and the paper's enamel-restoration results should not be attributed to this patent's chemistry. See Biomimetic Enamel Mineralization and Patent as Evidence.
Related pages
- US2018236130A1 — Amelogenin-Chitosan Hydrogel for Dentin Hypersensitivity — the other amelogenin-based patent in the dossier.
- Dental Enamel — the target tissue.
Source notes & attribution
- https://rexresearch.com/ChenHasanToothRegeneration/ChenHasanToothRegrowth.html